Early Detection & Biomarkers: Advances in blood-based biomarkers, neuroimaging, and genetic risk profiling (e.g., APOE status) for identifying preclinical disease stages.
Lifestyle Interventions: The impact of nutrition (Mediterranean/MIND diets), physical activity, sleep optimization, cognitive training, and social engagement on brain resilience.
Metabolic & Vascular Health: The role of insulin resistance, cardiovascular risk factors, inflammation, and gut–brain interactions in cognitive decline.
Pharmacological & Nutraceutical Approaches: Preventive use of anti-amyloid therapies, anti-inflammatory agents, NAD+ boosters, omega-3 fatty acids, and other neuroprotective compounds.
Precision & Personalized Prevention: Tailoring strategies based on genetics, epigenetics, and individual risk profiles.
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